Skip to main content

Search hotels in Santa Cruz de la Sierra

Enter your dates to see the latest prices and deals for Santa Cruz de la Sierra hotels

Santa Cruz de la Sierra – 665 hotels and places to stay

Show hotels on map

Filter by:

Star rating
Review score

Cosmopolitano Hotel Boutique

Hotel in Santa Cruz de la Sierra

Offering an outdoor pool, Cosmopolitano Hotel Boutique is located in the historical centre of Santa Cruz de la Sierra. Guests can enjoy the on-site bar.

E
Eliane
From
Brazil
I liked the decoration, the size, the fact that it was small, familiar, in summary, it was cosy. The bed is comfortable, and everything is very clean. The room is spacious, the idea of an integrated outdoor bathroom is interesting The staff is very pleasant, many of them were Brazilian. Always trying to be helpful and make our stay as pleasant as possible. As I left very early the next day, they insisted on providing me with breakfast early, outside the hotel's usual opening hours.
Scored out of 10, guest rating 9.1
Superb - What previous guests thought, 1,094 reviews
Price from
US$84.23
1 night, 2 adults
Check availability

TRYP by Wyndham Santa Cruz

Hotel in Santa Cruz de la Sierra

Situated in Santa Cruz de la Sierra, 1.6 km from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz features accommodation with an outdoor swimming pool, free private parking, a...

M
Marc
From
Singapore
Immaculately designed and maintained. Great reception staff.
Scored out of 10, guest rating 9.0
Superb - What previous guests thought, 603 reviews
Price from
US$69.30
1 night, 2 adults
Check availability

Hotel Cortez

Hotel in Santa Cruz de la Sierra

Boasting an outdoor swimming pool, gym and spa facilities, Hotel Cortez has chic and spacious rooms in Santa Cruz de la Sierra. Free WiFi access is available.

G
Graham
From
United Kingdom
Recently fully refurbished, the high standards and professionalism of the staff were only matched by their friendliness and helpfulness. Superb location, restaurants nearby. We stayed 14 nights, a fantastic 5 star experience in the middle of Santa Cruz.
Scored out of 10, guest rating 9.1
Superb - What previous guests thought, 229 reviews
Price from
US$180
1 night, 2 adults
Check availability

Lido Hotel

Hotel in Santa Cruz de la Sierra

Lido Hotel features accommodation in Santa Cruz de la Sierra near Metropolitan Cathedral and Gabriel Rene Moreno Autonomous University.

O
Ole
From
Denmark
Nice hotel a few blocks from the central square. The area is safe
Scored out of 10, guest rating 8.7
Fabulous - What previous guests thought, 122 reviews
Price from
US$44.05
1 night, 2 adults
Check availability

HOTEL OSHO

Hotel in Santa Cruz de la Sierra

Situated in Santa Cruz de la Sierra, 400 metres from Güembé Biocentre and Guazú Ivaga Park, HOTEL OSHO features accommodation with an outdoor swimming pool, free private parking, a fitness centre and...

F
Federica
From
Italy
Very nice and modern hotel, breakfast super with great fresh juices. Reception very nice and helpful
Scored out of 10, guest rating 8.2
Very good - What previous guests thought, 661 reviews
Price from
US$60.75
1 night, 2 adults
Check availability

ibis Santa Cruz de la Sierra

Hotel in Santa Cruz de la Sierra

Set in Santa Cruz de la Sierra, 1.3 km from Arenal Park, ibis Santa Cruz de la Sierra offers accommodation with a shared lounge, free private parking, a restaurant and a bar.

s
smith
From
China
breakfast is good, envirment is good
Scored out of 10, guest rating 8.9
Fabulous - What previous guests thought, 385 reviews
Price from
US$53.87
1 night, 2 adults
Check availability

Novotel Santa Cruz De La Sierra

Hotel in Santa Cruz de la Sierra

Set in Santa Cruz de la Sierra, 3.5 km from Gabriel Rene Moreno Autonomous University, Novotel Santa Cruz De La Sierra offers accommodation with an outdoor swimming pool, free private parking, a...

S
Stuart
From
United Kingdom
The hotel was very clean and modern. All of the staff were very accommodating and friendly.
Scored out of 10, guest rating 8.5
Very good - What previous guests thought, 192 reviews
Price from
US$94.50
1 night, 2 adults
Check availability

Chairu Eco Hotel

Hotel in Santa Cruz de la Sierra

Chairu Eco Hotel features a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra.

D
Deborah
From
United Kingdom
This was a brilliant hotel, clean and quiet. The staff and owner were superb. Anything we needed they supplied and even arranged a taxi when we were stranded in town. I would most definitely recommend and if we return in the future will book a room here again.
Scored out of 10, guest rating 8.9
Fabulous - What previous guests thought, 765 reviews
Price from
US$75
1 night, 2 adults
Check availability

Swissotel Santa Cruz de La Sierra

Hotel in Santa Cruz de la Sierra

Situated in Santa Cruz de la Sierra, 4.5 km from Gabriel Rene Moreno Autonomous University, Swissotel Santa Cruz de La Sierra features accommodation with an outdoor swimming pool, free private...

D
David
From
Argentina
All staff interactions were excellent.
Scored out of 10, guest rating 8.9
Fabulous - What previous guests thought, 267 reviews
Price from
US$133.20
1 night, 2 adults
Check availability

Marriott Santa Cruz de la Sierra Hotel

Hotel in Santa Cruz de la Sierra

Marriott Santa Cruz de la Sierra Hotel has an outdoor swimming pool, fitness centre, a shared lounge and terrace in Santa Cruz de la Sierra.

S
Stuart
From
United Kingdom
Excellent staff, very friendly and helpful. Clean hotel in a great location.
Scored out of 10, guest rating 8.9
Fabulous - What previous guests thought, 343 reviews
Price from
US$130.38
1 night, 2 adults
Check availability
See all 665 hotels in Santa Cruz de la Sierra

Hotels with airport shuttles in Santa Cruz de la Sierra

Hotel LP Santa Cruz Centro

Hotel in Santa Cruz de la Sierra
Airport shuttle (additional charge)
Scored out of 10, guest rating 8.4
Very good - What previous guests thought, 313 reviews
From US$68.02 per night

Mai Suites Apart Hotel

Hotel in Santa Cruz de la Sierra
Airport shuttle (additional charge)
Scored out of 10, guest rating 8.6
Fabulous - What previous guests thought, 166 reviews
From US$85 per night

Marriott Santa Cruz de la Sierra Hotel

Hotel in Santa Cruz de la Sierra
Airport shuttle (additional charge)
Scored out of 10, guest rating 8.9
Fabulous - What previous guests thought, 343 reviews
From US$122.18 per night

TRYP by Wyndham Santa Cruz

Hotel in Santa Cruz de la Sierra
Airport shuttle (additional charge)
Scored out of 10, guest rating 9.0
Superb - What previous guests thought, 603 reviews
From US$109 per night

HOTEL OSHO

Hotel in Santa Cruz de la Sierra
Airport shuttle (additional charge)
Scored out of 10, guest rating 8.2
Very good - What previous guests thought, 661 reviews
From US$65 per night

Cosmopolitano Hotel Boutique

Hotel in Santa Cruz de la Sierra
Airport shuttle (additional charge)
Scored out of 10, guest rating 9.1
Superb - What previous guests thought, 1,094 reviews
From US$106.29 per night

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Hotel in Santa Cruz de la Sierra
Airport shuttle (additional charge)
Scored out of 10, guest rating 8.8
Fabulous - What previous guests thought, 482 reviews
From US$134.10 per night

Novotel Santa Cruz De La Sierra

Hotel in Santa Cruz de la Sierra
Airport shuttle (additional charge)
Scored out of 10, guest rating 8.5
Very good - What previous guests thought, 192 reviews
From US$105 per night

Hotel Cortez

Hotel in Santa Cruz de la Sierra
Airport shuttle (additional charge)
Scored out of 10, guest rating 9.1
Superb - What previous guests thought, 229 reviews
From US$180 per night

Hotel Sirari By Regina

Hotel in Santa Cruz de la Sierra
Airport shuttle (additional charge)
Scored out of 10, guest rating 8.4
Very good - What previous guests thought, 221 reviews
From US$115 per night

Most booked hotels in Santa Cruz de la Sierra and surroundings in the past month

See all

Popular with guests booking hotels in Santa Cruz de la Sierra

Scored out of 10, guest rating 7.4
Good - What previous guests thought, 158 reviews

Popular with guests booking hotels in Santa Cruz de la Sierra

Scored out of 10, guest rating 6.6
Pleasant - What previous guests thought, 251 reviews

Popular with guests booking hotels in Santa Cruz de la Sierra

Scored out of 10, guest rating 8.7
Fabulous - What previous guests thought, 343 reviews

Popular with guests booking hotels in Santa Cruz de la Sierra

Scored out of 10, guest rating 8.7
Fabulous - What previous guests thought, 674 reviews

Popular with guests booking hotels in Santa Cruz de la Sierra

Scored out of 10, guest rating 9.1
Superb - What previous guests thought, 1,094 reviews

Popular with guests booking hotels in Santa Cruz de la Sierra

Scored out of 10, guest rating 7.6
Good - What previous guests thought, 506 reviews

Popular with guests booking hotels in Santa Cruz de la Sierra

Scored out of 10, guest rating 8.8
Fabulous - What previous guests thought, 482 reviews

Popular with guests booking hotels in Santa Cruz de la Sierra

Scored out of 10, guest rating 9.0
Superb - What previous guests thought, 603 reviews

Popular with guests booking hotels in Santa Cruz de la Sierra

Scored out of 10, guest rating 8.2
Very good - What previous guests thought, 665 reviews

Popular with guests booking hotels in Santa Cruz de la Sierra

Scored out of 10, guest rating 8.9
Fabulous - What previous guests thought, 385 reviews

Best hotels with breakfast in Santa Cruz de la Sierra and nearby

Scored out of 10, guest rating 7.7
Good - What previous guests thought, 218 reviews

Located in Santa Cruz de la Sierra, 300 metres from 24th of September Metropolitan Plaza, Hotel Viru Viru provides accommodation with a restaurant, private parking, an outdoor swimming pool and a...

From US$44 per night
Scored out of 10, guest rating 7.4
Good - What previous guests thought, 170 reviews

Featuring a swimming pool, a fitness centre and a restaurant, Hotel Arenal offers rooms with free Wi-Fi and flat-screen TVs in Santa Cruz de la Sierra. Free parking is provided.

From US$69.90 per night
Scored out of 10, guest rating 7.7
Good - What previous guests thought, 1,059 reviews

Featuring an outdoor pool, La Siesta Hotel offers accommodations in Santa Cruz de la Sierra. Free WiFi access is available.

From US$74.58 per night
Scored out of 10, guest rating 8.5
Very good - What previous guests thought, 348 reviews

Located within 600 metres of 24th of September Metropolitan Plaza and 800 metres of Sacred Art Museum, Buen Retiro Apart Hotel provides rooms with air conditioning and a private bathroom in Santa Cruz...

From US$45 per night
Scored out of 10, guest rating 8.7
Fabulous - What previous guests thought, 122 reviews

Lido Hotel features accommodation in Santa Cruz de la Sierra near Metropolitan Cathedral and Gabriel Rene Moreno Autonomous University.

From US$44.05 per night
Scored out of 10, guest rating 7.4
Good - What previous guests thought, 158 reviews

Situated in Santa Cruz de la Sierra, 800 metres from Sacred Art Museum, Ex Hotel Asturias Centrico features accommodation with an outdoor swimming pool, free private parking, a garden and a terrace.

From US$26.68 per night
Scored out of 10, guest rating 8.5
Very good - What previous guests thought, 140 reviews

Set in Santa Cruz de la Sierra, less than 1 km from Arenal Park, Adventure 360º Hostel offers accommodation with a fitness centre, private parking, a shared lounge and a terrace.

From US$26 per night
Scored out of 10, guest rating 8.6
Fabulous - What previous guests thought, 32 reviews

Located in Santa Cruz de la Sierra, 1.5 km from 24th of September Metropolitan Plaza, Hotel el super 8 provides accommodation with a garden, free private parking, a terrace and a restaurant.

From US$33 per night

Hotels located in the centre of Santa Cruz de la Sierra

Scored out of 10, guest rating 7.1
Good - What previous guests thought, 53 reviews

Located in Santa Cruz de la Sierra, 100 metres from Sacred Art Museum, Pascana Hotel provides accommodation with an outdoor swimming pool, free private parking, a terrace and a restaurant.

From US$56.10 per night
Scored out of 10, guest rating 1.0
Bad - What previous guests thought, 1 review

Habitación cercana al centro de la ciudad is situated in Santa Cruz de la Sierra, 500 metres from Metropolitan Cathedral, 500 metres from 24th of September Metropolitan Plaza, and 700 metres from...

From US$15 per night

Situated in Santa Cruz de la Sierra, near Metropolitan Cathedral, 24th of September Metropolitan Plaza and Arenal Park, Hostal Center features a terrace.

From US$20 per night

Set within 300 metres of Sacred Art Museum and 400 metres of Metropolitan Cathedral, Amaca Hostal offers rooms with air conditioning and a private bathroom in Santa Cruz de la Sierra.

From US$18 per night

Located in Santa Cruz de la Sierra, within 300 metres of Sacred Art Museum and 400 metres of Metropolitan Cathedral, Hostal Independencia provides accommodation with a terrace and free WiFi throughout...

From US$21 per night
Scored out of 10, guest rating 1.0
Bad - What previous guests thought, 2 reviews

Hostal independencia is situated in Santa Cruz de la Sierra, 300 metres from Sacred Art Museum, 400 metres from Metropolitan Cathedral, as well as 400 metres from 24th of September Metropolitan Plaza.

From US$21 per night

Hostal independencia is located in Santa Cruz de la Sierra, within 1 km of Arenal Park and 3.6 km of Güembé Biocentre and Guazú Ivaga Park.

From US$20 per night

Located in Santa Cruz de la Sierra, 600 metres from 24th of September Metropolitan Plaza and 800 metres from Sacred Art Museum, Sarao 2 offers air conditioning. A hot tub is available for guests.

From US$38.25 per night

Budget hotels in Santa Cruz de la Sierra and nearby

Scored out of 10, guest rating 9.7
Exceptional - What previous guests thought, 3 reviews

Located in Santa Cruz de la Sierra, 400 metres from Sacred Art Museum and 500 metres from Metropolitan Cathedral, Departmento Ametauna provides spacious air-conditioned accommodation with a balcony...

From US$54 per night
Scored out of 10, guest rating 8.9
Fabulous - What previous guests thought, 17 reviews

Set in Santa Cruz de la Sierra, 500 metres from Sacred Art Museum, Santa Cruz Home features a terrace and views of the city.

From US$24 per night
Scored out of 10, guest rating 8.6
Fabulous - What previous guests thought, 146 reviews

Pacifico Apart Hotel is a property with a rooftop pool, set in Santa Cruz de la Sierra, within just 1.1 km of Arenal Park and 1.4 km of Güembé Biocentre and Guazú Ivaga Park.

From US$44.20 per night
Scored out of 10, guest rating 8.0
Very good - What previous guests thought, 11 reviews

Located in Santa Cruz de la Sierra, within 1.2 km of Güembé Biocentre and Guazú Ivaga Park and 1.6 km of 24th of September Metropolitan Plaza, Gaman Hotel Glamping provides accommodation with a garden...

From US$65 per night
Scored out of 10, guest rating 8.6
Fabulous - What previous guests thought, 68 reviews

Situated in Santa Cruz de la Sierra, 1.2 km from Güembé Biocentre and Guazú Ivaga Park, Lili's Hostel features accommodation with an outdoor swimming pool, free private parking and a garden.

Scored out of 10, guest rating 8.1
Very good - What previous guests thought, 22 reviews

Boasting air-conditioned accommodation with a balcony, Luxury Apartment -3 bedrooms is situated in Santa Cruz de la Sierra.

From US$71 per night
Scored out of 10, guest rating 8.9
Fabulous - What previous guests thought, 385 reviews

Set in Santa Cruz de la Sierra, 1.3 km from Arenal Park, ibis Santa Cruz de la Sierra offers accommodation with a shared lounge, free private parking, a restaurant and a bar.

From US$72 per night
Scored out of 10, guest rating 7.8
Good - What previous guests thought, 79 reviews

Situated in Santa Cruz de la Sierra, less than 1 km from Gabriel Rene Moreno Autonomous University, Santa Limbania Boutique Hotel features accommodation with an outdoor swimming pool, free private...

From US$45 per night

FAQs about hotels in Santa Cruz de la Sierra

What guests said about Santa Cruz de la Sierra:

4.0

The travel agencies across this town works very...

The travel agencies across this town works very inefficiently, this cost both time, money and jobs. I would have loved to pay for the private tour to Lomas, Ambrosa and the Inka, but as you know, nothing works properly in this town. The city itself is safe but boring.
Guest review by
Benji
Denmark
6.0

It's a city with not much to offer.

It's a city with not much to offer. You're better off in La Paz, where the views are nicer, the scenery is just better. But you're really much better off in the more rural places, in the mountains, by the lakes and away from the cities.
Guest review by
Ognyan
United Kingdom
8.0

Santa Cruz de la Sierra is an interesting city with a busy...

Santa Cruz de la Sierra is an interesting city with a busy and parcely old part downtown. You find museums, the main plaza with the cathedral, shops for everyone, big restaurants and small places who sell delicious local food. Also thera are some modern shopping malls as also black markets where you find everything you might need for living. Cultural events are offered and some really nice places with abundant semi-tropical vegetation as well as places with a lake to swim and hotels. You can take a taxi or go by bus to almost every place you like, in general it is very safe, only in the outskirts you should be more careful and maybe not go there at nigt. Always take your purse with important things in front of you - just in case! I certainly recommend Santa Cruz for a visit! A little bit outside there are the sanddunes and the botanical garden and other places like the Chiquitania, also very worth visiting!
Guest review by
Cornelia
Germany
8.0

Friendly people (is famous for its hospitality).

Friendly people (is famous for its hospitality). Is the most productive area of the country, you can find everything you expect of a big city. I like my staying and I will be back with more time and better organized agenda. Given the size of the city and the weather (mostly humid and hot) a car is necessary to visit properly Santa Cruz.
Guest review by
Flavio David Y.
Bolivia
4.0

Nothing much to see in Santa Cruz, especially if you want to...

Nothing much to see in Santa Cruz, especially if you want to avoid catching Dengue Fever. I avoided traveling to more rural areas or even to the botanical gardens due to the high number of dengue cases there. In the city itself there's very little to see, although the nicer parts have some decent-looking restaurants and bars, so maybe during the dry season (less mosquitos) it might be a nice place to relax.
Guest review by
Liron
United Kingdom
8.0

Santa cruz has a old historic center, a bit dangerous.

Santa cruz has a old historic center, a bit dangerous. Better to stay in the modern hotel district of Avenida San Martin, locals call this the VIP zone. Many nice restaurants and cafes, stores, boutiques and shopping malls. I highly suggest you visit the jesuit mision area! The five day circuit is perfect to see all the misions.
Guest review by
Mariela
United States

See reviews by guests who stayed at hotels in Santa Cruz de la Sierra

See all

Comodo y lujos monoambiente Equipetrol NanoTec

Santa Cruz de la Sierra
Scored out of 10, guest rating 9.7
Exceptional - What previous guests thought, 42 reviews
Highly recommend! Great value for money, and they charge the official rate in bolivianos. Easy communication with the host via WhatsApp. The apartment was brand new, extremely clean and modern, in the safe upscale neighbourhood of Equipetrol. Lots of shops, bars and restaurants around. Great city views. Santa Cruz is extremely hot, so the strong A/C and beautiful rooftop pool area were really appreciated. The reception staff stored our luggage for a few hours after we checked out which was a great help.
Guest review by
Michael
Australia

Chairu Eco Hotel

Santa Cruz de la Sierra
From US$80 per night
Scored out of 10, guest rating 8.9
Fabulous - What previous guests thought, 765 reviews
This was a brilliant hotel, clean and quiet. The staff and owner were superb. Anything we needed they supplied and even arranged a taxi when we were stranded in town. I would most definitely recommend and if we return in the future will book a room here again.
Guest review by
Deborah
United Kingdom

Hotel America

Santa Cruz de la Sierra
Scored out of 10, guest rating 7.9
Good - What previous guests thought, 902 reviews
Lovely hotel in the centre of the city. Staff very friendly and helpful. I arrived at 2 in the morning.and the night porter let me book in for a small fee. The room was spacious and clean and comfortable
Guest review by
Marcus
Ireland

Marriott Santa Cruz de la Sierra Hotel

Santa Cruz de la Sierra
From US$122.18 per night
Scored out of 10, guest rating 8.9
Fabulous - What previous guests thought, 343 reviews
Very corporate but after travelling around Bolivia for a week it was like a shining beacon of luxury - a good Marriott great pool and room and English speaking reception 🤗
Guest review by
Helen
United Kingdom

Lido Hotel

Santa Cruz de la Sierra
From US$44.05 per night
Scored out of 10, guest rating 8.7
Fabulous - What previous guests thought, 122 reviews
The staff at the hotel were very helpful. The location of the hotel is great, close to most attractions in the city centre
Guest review by
Stephen
Canada

Research, refine and make plans for your whole trip

Flights from London to Santa Cruz de la Sierra

Find and compare the best flights for your trip to Santa Cruz de la Sierra right here on Booking.com.

Hotels near Viru Viru International Airport

Perfect for a late arrival or early departure.

Car hire in Santa Cruz de la Sierra

Hire a car and hit the road.

Hotels in La Paz

Discover another destination in Bolivia.

Hotels in Copacabana

Discover another destination in Bolivia.

Apartments in Santa Cruz de la Sierra

More great accommodation options for your trip.

Cheap hotels in Santa Cruz de la Sierra

Explore more great accommodation options in Santa Cruz de la Sierra, starting with cheap hotels.

Serviced Apartments in Santa Cruz de la Sierra

More great accommodation options for your trip.

Guest Houses in Santa Cruz de la Sierra

More great accommodation options for your trip.