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Stay in Santa Cruz Region's best hotels!

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Wonderful: 9+ Very Good: 8+ Good: 7+ Pleasant: 6+
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Chairu Eco Hotel

Hotel in Santa Cruz de la Sierra

Chairu Eco Hotel features a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra. This 4-star hotel offers a concierge service and a tour desk. Everything was good. The great and super helpful staff made the stay perfect

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9
Wonderful
832 reviews
Price from
$50.16
per night

TRYP by Wyndham Santa Cruz

Hotel in Santa Cruz de la Sierra

Located in Santa Cruz de la Sierra, a 19-minute walk from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz has accommodations with an outdoor swimming pool, free private parking,... Immaculately designed and maintained. Great reception staff.

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9
Wonderful
431 reviews
Price from
$67.15
per night

YVY CASA HOTEL

Hotel in Samaipata

Located in Samaipata, 6.1 miles from Samaipata Fort, YVY CASA HOTEL provides accommodations with a garden, free private parking and a terrace. Beautiful, original, lovely surroundings, great people!!

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9.2
Wonderful
262 reviews
Price from
$42.75
per night

Marriott Santa Cruz de la Sierra Hotel

Hotel in Santa Cruz de la Sierra

Marriott Santa Cruz de la Sierra Hotel has an outdoor swimming pool, fitness center, a shared lounge and terrace in Santa Cruz de la Sierra. the staff was exceptionally well trained, kindly and helpful

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9.1
Wonderful
312 reviews
Price from
$102.40
per night

Cosmopolitano Hotel Boutique

Hotel in Santa Cruz de la Sierra

Offering an outdoor pool, Cosmopolitano Hotel Boutique is located in the historical center of Santa Cruz de la Sierra. Guests can enjoy the on-site bar. Absolutely everything! Best hotel and service

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9.1
Wonderful
883 reviews
Price from
$84.59
per night

La Vida es Bella

Hotel in Samaipata

Located in Samaipata, 5.6 miles from Samaipata Fort, La Vida es Bella provides accommodations with a garden, free private parking, a shared lounge and a terrace. Great location. Wonderful service. The best breakfast ever. A perfect place to rest and enjoy Samaipata.

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9.3
Wonderful
114 reviews
Price from
$60
per night

El Pueblito Hotel Boutique

Hotel in Samaipata

Located in Samaipata, 7 miles from Samaipata Fort, El Pueblito Hotel Boutique has accommodations with an outdoor swimming pool, free private parking, a garden and a shared lounge. We loved the charm, comfort and friendly, helpful staff.

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9.5
Exceptional
223 reviews
Price from
$87
per night

Alfonsina Hotel Boutique

Hotel in Santa Cruz de la Sierra

Conveniently located only a 10-minute walk from Ventura Shopping Center, Alfonsina Hotel Boutique. offers accommodations in Santa Cruz de la Sierra. Very beautiful hotel in Santa Cruz. The room we had was spacious, very comfortable and clean - and nicely decorated with lots of cinema references.The breakfast was delicious too. The hotel is a bit off from the historic center but it is a short ride or a slightly longer walk. We would definitely come back and stay here again!

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9.4
Wonderful
388 reviews
Price from
$94.50
per night

Suite 5 Estrellas

Hotel in Santa Cruz de la Sierra

Located 1.3 miles from Gabriel Rene Moreno Autonomous University, Suite 5 Estrellas offers 5-star accommodations in Santa Cruz de la Sierra and has a garden, a restaurant and a bar.

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9.2
Wonderful
5 reviews
Price from
$28
per night

Hostal Juanita

Hotel in Vallegrande

Hostal Juanita is offering accommodations in Vallegrande. This 1-star hotel offers a shared lounge and room service. There's a terrace and guests can use free WiFi and free private parking. Centrally located. Beautifully decorated. Comfortable bed. Hot shower. Good Wi-Fi. Flexible checkout. Delicious breakfast. And very friendly and helpful staff (two sisters).

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9
Wonderful
10 reviews
Price from
$26
per night

Hotels with extra health and safety measures

Find hotels in Santa Cruz Region with added hygiene measures plus high cleanliness ratings

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Cleanliness & disinfection
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Most-booked hotels in Santa Cruz Region in the past month

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Santa Cruz Region's best hotels with breakfast

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